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Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome
RNA interference (RNAi) is a conserved RNA silencing pathway that leads to sequence-specific mRNA decay in response to the presence of double-stranded RNA (dsRNA). Long dsRNA molecules are first processed by Dicer into 21–22-nucleotide small interfering RNAs (siRNAs). The siRNAs are incorporated int...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2005 by RNA Society
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370735/ https://ncbi.nlm.nih.gov/pubmed/15703439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7231505 |
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