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Structural probing of a pathogenic tRNA dimer

The A3243G mutation within the human mitochondrial (hs mt) tRNA(Leu(UUR)) gene is associated with maternally inherited deafness and diabetes (MIDD) and other mitochondrial encephalopathies. One of the most pronounced structural effects of this mutation is the disruption of the native structure throu...

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Detalles Bibliográficos
Main Authors: ROY, MARC D., WITTENHAGEN, LISA M., KELLEY, SHANA O.
Formato: Artigo
Idioma:Inglês
Publicado: Copyright 2005 by RNA Society 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370715/
https://ncbi.nlm.nih.gov/pubmed/15701731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7143305
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