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A single residue in LeuRS affecting amino acid specificity and tRNA aminoacylation
Human mitochondrial leucyl-tRNA synthetase (hs mt LeuRS) achieves high aminoacylation fidelity without a functional editing active site, representing a rare example of a class I aminoacyl-tRNA synthetase (aaRS) that does not proofread its products. Previous studies demonstrated that the enzyme achie...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518062/ https://ncbi.nlm.nih.gov/pubmed/17378584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0618215 |
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