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The pathogenic U3271C human mitochondrial tRNA(Leu(UUR)) mutation disrupts a fragile anticodon stem

The U3271C mutation affecting the human mitochondrial transfer RNA(Leu(UUR)) (hs mt tRNA) is correlated with diabetes and mitochondrial encephalopathies. We have explored the relationship between the structural effects of this mutation and its impact on function using chemical probing experiments an...

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Sonraí Bibleagrafaíochta
Main Authors: Wittenhagen, Lisa M., Roy, Marc D., Kelley, Shana O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC140497/
https://ncbi.nlm.nih.gov/pubmed/12527767
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