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U2AF binding selects for the high conservation of the C. elegans 3′ splice site
Caenorhabditis elegans is unusual among animals in having a highly conserved octamer sequence at the 3′ splice site: UUUU CAG/R. This sequence can bind to the essential heterodimeric splicing factor U2AF, with U2AF(65) contacting the U tract and U2AF(35) contacting the splice site itself (AG/R). Her...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Copyright 2005 by RNA Society
2005
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370714/ https://ncbi.nlm.nih.gov/pubmed/15661845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7221605 |
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