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The snRNP 15.5K protein folds its cognate K-turn RNA: A combined theoretical and biochemical study

The human 15.5K protein binds to the 5′ stem–loop of U4 snRNA, promotes the assembly of the spliceosomal U4/U6 snRNP, and is required for the recruitment of the 61K protein and the 20/60/90K protein complex to the U4 snRNA. In the crystallographic structure of the 15.5K–U4 snRNA complex, the conform...

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Detalhes bibliográficos
Main Authors: COJOCARU, VLAD, NOTTROTT, STEPHANIE, KLEMENT, REINHARD, JOVIN, THOMAS M.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370708/
https://ncbi.nlm.nih.gov/pubmed/15659359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7149605
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