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Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability

A key issue in the nucleotide excision repair (NER) of bulky carcinogen–DNA adducts is the ability of the NER machinery to recognize and repair certain adducts while failing to repair others. Unrepaired adducts can survive to cause mutations that initiate the carcinogenic process. Benzo[c]phenanthre...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Wu, Min, Yan, Shixiang, Patel, Dinshaw J., Geacintov, Nicholas E., Broyde, Suse
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12140327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf427
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