Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability

A key issue in the nucleotide excision repair (NER) of bulky carcinogen–DNA adducts is the ability of the NER machinery to recognize and repair certain adducts while failing to repair others. Unrepaired adducts can survive to cause mutations that initiate the carcinogenic process. Benzo[c]phenanthre...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Wu, Min, Yan, Shixiang, Patel, Dinshaw J., Geacintov, Nicholas E., Broyde, Suse
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2002
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12140327/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf427
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