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Analysis of 2′-phosphotransferase (Tpt1p) from Saccharomyces cerevisiae: Evidence for a conserved two-step reaction mechanism
Tpt1p is an essential protein responsible for the 2′-phosphotransferase step of tRNA splicing in Saccharomyces cerevisiae, in which the splice junction 2′-phosphate of ligated tRNA is transferred to NAD to form mature tRNA and ADP-ribose 1″-2″ cyclic phosphate. We showed previously that Tpt1p is a m...
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| Format: | Artigo |
| Sprache: | Inglês |
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Copyright 2005 by RNA Society
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370695/ https://ncbi.nlm.nih.gov/pubmed/15611300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7194605 |
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