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Intracellular folding of the Tetrahymena group I intron depends on exon sequence and promoter choice

The Tetrahymena group I intron splices 20 to 50 times faster in Tetrahymena than in vitro, implying that the intron rapidly adopts its active conformation in the cell. The importance of cotranscriptional folding and the contribution of the rRNA exons to the stability of the active pre-RNA structure...

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Bibliographic Details
Main Authors: KODUVAYUR, SUJATHA P., WOODSON, SARAH A.
Format: Artigo
Language:Inglês
Published: Copyright 2004 by RNA Society 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370639/
https://ncbi.nlm.nih.gov/pubmed/15337845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7880404
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