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Refolding of rRNA exons enhances dissociation of the Tetrahymena intron.

Self-splicing of the Tetrahymena pre-rRNA is inhibited by a conserved rRNA hairpin P(-1) upstream of the 5' splice site. P(-1) inhibits self-splicing by competing with formation of the P1 splice site helix. Here we show that the P(-1) hairpin also enhances dissociation of the spliced products,...

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Détails bibliographiques
Auteurs principaux: Cao, Y, Woodson, S A
Format: Artigo
Langue:Inglês
Publié: 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369998/
https://ncbi.nlm.nih.gov/pubmed/10999602
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