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Intracellular folding of the Tetrahymena group I intron depends on exon sequence and promoter choice

The Tetrahymena group I intron splices 20 to 50 times faster in Tetrahymena than in vitro, implying that the intron rapidly adopts its active conformation in the cell. The importance of cotranscriptional folding and the contribution of the rRNA exons to the stability of the active pre-RNA structure...

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書目詳細資料
Main Authors: KODUVAYUR, SUJATHA P., WOODSON, SARAH A.
格式: Artigo
語言:Inglês
出版: Copyright 2004 by RNA Society 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370639/
https://ncbi.nlm.nih.gov/pubmed/15337845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7880404
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