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Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements

It has been shown that the activity of the hammerhead ribozyme at μM magnesium ion concentrations is markedly increased by the inclusion of loops in helices I and II. We have studied the effect of such loops on the magnesium ion-induced folding of the ribozyme, using fluorescence resonance energy tr...

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Bibliografische gegevens
Hoofdauteurs: PENEDO, J. CARLOS, WILSON, TIMOTHY J., JAYASENA, SUMEDHA D., KHVOROVA, ANASTASIA, LILLEY, DAVID M.J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Copyright 2004 by RNA Society 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370577/
https://ncbi.nlm.nih.gov/pubmed/15100442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5268404
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