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Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements

It has been shown that the activity of the hammerhead ribozyme at μM magnesium ion concentrations is markedly increased by the inclusion of loops in helices I and II. We have studied the effect of such loops on the magnesium ion-induced folding of the ribozyme, using fluorescence resonance energy tr...

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Autori principali: PENEDO, J. CARLOS, WILSON, TIMOTHY J., JAYASENA, SUMEDHA D., KHVOROVA, ANASTASIA, LILLEY, DAVID M.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2004 by RNA Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370577/
https://ncbi.nlm.nih.gov/pubmed/15100442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5268404
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