Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

microRNAs (miRNAs) are widespread among eukaryotes, and studies in several systems have revealed that miRNAs can regulate expression of specific genes. Primary miRNA transcripts are initially processed to ≈70-nucleotide (nt) stem–loop structures (pre-miRNAs), exported to the cytoplasm, further proce...

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Autores principales: BOHNSACK, MARKUS T., CZAPLINSKI, KEVIN, GÖRLICH, DIRK
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2004 by RNA Society 2004
Materias:
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370530/
https://ncbi.nlm.nih.gov/pubmed/14730017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5167604
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