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Identification of Amino Acid Residues of gp130 Signal Transducer and gp80 α Receptor Subunit That Are Involved in Ligand Binding and Signaling by Human Herpesvirus 8-Encoded Interleukin-6

Human herpesvirus 8-encoded interleukin-6 (vIL-6) signals through the gp130 signal transducer but is not dependent on the IL-6 receptor α subunit (IL-6R, gp80) that is required for signaling by endogenous IL-6 proteins; however, IL-6R can enhance vIL-6 activity and can enable signaling through a gp1...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Hong, Nicholas, John
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC137051/
https://ncbi.nlm.nih.gov/pubmed/11991991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.11.5627-5636.2002
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