Pivotal Role of the Non-hr Origin of DNA Replication in the Genesis of Defective Interfering Baculoviruses

The generation of deletion mutants, including defective interfering viruses, upon serial passage of Spodoptera exigua multicapsid nucleopolyhedrovirus (SeMNPV) in insect cell culture has been studied. Sequences containing the non-homologous region origin of DNA replication (non-hr ori) became hyperm...

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Autors principals: Pijlman, Gorben P., Dortmans, Jos C. F. M., Vermeesch, Angela M. G., Yang, Kai, Martens, Dirk E., Goldbach, Rob W., Vlak, Just M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137048/
https://ncbi.nlm.nih.gov/pubmed/11991989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.11.5605-5611.2002
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