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Cleavage at the Furin Consensus Sequence RAR/KR(109) and Presence of the Intervening Peptide of the Respiratory Syncytial Virus Fusion Protein Are Dispensable for Virus Replication in Cell Culture

Proteolytic processing of the respiratory syncytial virus F (fusion) protein results in the generation of the disulfide-linked subunits F1 and F2 and in the release of pep27, a glycopeptide originally located between the two furin cleavage sites FCS-1 (RKRR(136)) and FCS-2 (RAR/KR(109)). We made use...

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Bibliografski detalji
Glavni autori: Zimmer, Gert, Conzelmann, Karl-Klaus, Herrler, Georg
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136468/
https://ncbi.nlm.nih.gov/pubmed/12186905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.18.9218-9224.2002
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