Cleavage at the Furin Consensus Sequence RAR/KR(109) and Presence of the Intervening Peptide of the Respiratory Syncytial Virus Fusion Protein Are Dispensable for Virus Replication in Cell Culture

Proteolytic processing of the respiratory syncytial virus F (fusion) protein results in the generation of the disulfide-linked subunits F1 and F2 and in the release of pep27, a glycopeptide originally located between the two furin cleavage sites FCS-1 (RKRR(136)) and FCS-2 (RAR/KR(109)). We made use...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Zimmer, Gert, Conzelmann, Karl-Klaus, Herrler, Georg
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136468/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12186905/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.18.9218-9224.2002
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