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Monoclonal antibodies targeting sites in respiratory syncytial virus attachment G protein provide protection against RSV-A and RSV-B in mice

Abstract Currently, only Palivizumab and Nirsevimab that target the respiratory syncytical virus (RSV) fusion protein are licensed for pre-treatment of infants. Glycoprotein-targeting antibodies may also provide protection against RSV. In this study, we generate monoclonal antibodies from mice immun...

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Главные авторы: Youri Lee, Laura Klenow, Elizabeth M. Coyle, Gabrielle Grubbs, Hana Golding, Surender Khurana
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Portfolio 2024-04-01
Серии:Nature Communications
Online-ссылка:https://doi.org/10.1038/s41467-024-47146-2
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