A Nucleotide Substitution in the tRNA(Lys) Primer Binding Site Dramatically Increases Replication of Recombinant Simian Immunodeficiency Virus Containing a Human Immunodeficiency Virus Type 1 Reverse Transcriptase
A recombinant simian immunodeficiency virus (SIV) derived from strain 239 (SIVmac239) with reverse transcriptase (RT) sequences from human immunodeficiency virus type 1 (HIV-1) strain HXB2 was severely impaired for replication. Detectable p27(Gag) levels were not observed until day 65 and peak p27(G...
محفوظ في:
| الحاوية / القاعدة: | J Virol |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
2002
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11992009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.11.5803-5806.2002 |
| الوسوم: |
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