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An siRNA ribonucleoprotein is found associated with polyribosomes in Trypanosoma brucei

Genetic interference by double-stranded RNA (dsRNA) or RNA interference (RNAi) triggers the sequence-specific degradation of cellular transcripts. The mediators of mRNA degradation are small interfering RNAs (siRNAs). Here, we report that in Trypanosoma brucei, 10%–20% of siRNAs cosediment with poly...

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Detalles Bibliográficos
Main Authors: DJIKENG, APPOLINAIRE, SHI, HUAFANG, TSCHUDI, CHRISTIAN, SHEN, SHUIYUAN, ULLU, ELISABETTA
Formato: Artigo
Idioma:Inglês
Publicado: Copyright 2003 by RNA Society 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370447/
https://ncbi.nlm.nih.gov/pubmed/12810914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5270203
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