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Sequence requirements for micro RNA processing and function in human cells

Most eukaryotes encode a substantial number of small noncoding RNAs termed micro RNAs (miRNAs). Previously, we have demonstrated that miR-30, a 22-nucleotide human miRNA, can be processed from a longer transcript bearing the proposed miR-30 stem-loop precursor and can translationally inhibit an mRNA...

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Main Authors: ZENG, YAN, CULLEN, BRYAN R.
Formato: Artigo
Idioma:Inglês
Publicado: Copyright 2003 by RNA Society 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370375/
https://ncbi.nlm.nih.gov/pubmed/12554881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2780503
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