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Characterization of human Smg5/7a: A protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1
Nonsense-mediated mRNA decay (NMD) in mammalian cells depends on phosphorylation of Upf1, an RNA-dependent ATPase and 5′-to-3′ helicase. Upf1 phosphorylation is mediated by Smg1, a phosphoinositol 3-kinase–related protein kinase. Here, we describe a human protein, which we call hSmg5/7a, that manife...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Copyright 2003 by RNA Society
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370372/ https://ncbi.nlm.nih.gov/pubmed/12554878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2137903 |
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