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The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly.

In the pre-mRNA processing machinery of eukaryotic cells, U6 snRNA is located at or near the active site for pre-mRNA splicing catalysis, and U6 is involved in catalyzing the first chemical step of splicing. We have further defined the roles of key features of yeast U6 snRNA in the splicing process....

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Autors principals: Ryan, Daniel E, Abelson, John
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370321/
https://ncbi.nlm.nih.gov/pubmed/12212854
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