Synthesis and properties of mRNAs containing the novel "anti-reverse" cap analogs 7-methyl(3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG.

The ability to synthesize capped RNA transcripts in vitro using bacteriophage polymerases has been of considerable value in a variety of applications. However, Pasquinelli et al. [RNA (1995) 1:957-967] found that one-third to one-half of the caps are incorporated in the reverse orientation, that is,...

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Библиографические подробности
Главные авторы: Stepinski, J, Waddell, C, Stolarski, R, Darzynkiewicz, E, Rhoads, R E
Формат: Artigo
Язык:Inglês
Опубликовано: 2001
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370192/
https://ncbi.nlm.nih.gov/pubmed/11680853
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