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Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex
The heterodimeric nuclear cap-binding complex (CBC) binds to the 5′ cap structure of RNAs in the nucleus and plays a central role in their diverse maturation steps. We describe the crystal structure at 2.1 Å resolution of human CBC bound to an m(7)GpppG cap analogue. Comparison with the structure of...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129070/ https://ncbi.nlm.nih.gov/pubmed/12374755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf538 |
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