Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex
The heterodimeric nuclear cap-binding complex (CBC) binds to the 5′ cap structure of RNAs in the nucleus and plays a central role in their diverse maturation steps. We describe the crystal structure at 2.1 Å resolution of human CBC bound to an m(7)GpppG cap analogue. Comparison with the structure of...
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| Vydáno v: | EMBO J |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374755/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf538 |
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