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A minihelix-loop RNA acts as a trans-aminoacylation catalyst.

We previously reported a bifunctional ribozyme that catalyzes self-aminoacylation and subsequent acyl-transfer to a tRNA. The ribozyme selectively recognizes a biotinyl-glutamine substrate, and charges the tRNA molecule in trans. Structurally, there are two catalytic domains, referred to as glutamin...

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Bibliografische gegevens
Hoofdauteurs: Lee, N, Suga, H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2001
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370145/
https://ncbi.nlm.nih.gov/pubmed/11453065
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