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An in vitro evolved precursor tRNA with aminoacylation activity

A set of catalysts for aminoacyl-tRNA synthesis is an essential component for translation. The RNA world hypothesis postulates that RNA catalysts could have played this role. Here we show an in vitro evolved precursor tRNA consisting of two domains, a catalytic 5′-leader sequence and an aminoacyl-ac...

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書誌詳細
主要な著者: Saito, Hirohide, Kourouklis, Dimitrios, Suga, Hiroaki
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC145511/
https://ncbi.nlm.nih.gov/pubmed/11285242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1797
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