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An in vitro evolved precursor tRNA with aminoacylation activity

A set of catalysts for aminoacyl-tRNA synthesis is an essential component for translation. The RNA world hypothesis postulates that RNA catalysts could have played this role. Here we show an in vitro evolved precursor tRNA consisting of two domains, a catalytic 5′-leader sequence and an aminoacyl-ac...

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Detalhes bibliográficos
Main Authors: Saito, Hirohide, Kourouklis, Dimitrios, Suga, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC145511/
https://ncbi.nlm.nih.gov/pubmed/11285242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.7.1797
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