An in vitro evolved precursor tRNA with aminoacylation activity

A set of catalysts for aminoacyl-tRNA synthesis is an essential component for translation. The RNA world hypothesis postulates that RNA catalysts could have played this role. Here we show an in vitro evolved precursor tRNA consisting of two domains, a catalytic 5′-leader sequence and an aminoacyl-ac...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Saito, Hirohide, Kourouklis, Dimitrios, Suga, Hiroaki
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2001
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11285242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.7.1797
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