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Principles of chemical geometry underlying chiral selectivity in RNA minihelix aminoacylation

The origin of homochirality in L-amino acid in proteins is one of the mysteries of the evolution of life. Experimental studies show that a non-enzymatic aminoacylation reaction of an RNA minihelix has a preference for L-amino acid over D-amino acid. The reaction initiates by approaching of a 3′-oxyg...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Ando, Tadashi, Takahashi, Shunichi, Tamura, Koji
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265448/
https://ncbi.nlm.nih.gov/pubmed/30321374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky909
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