Optimization and optimality of a short ribozyme ligase that joins non-Watson-Crick base pairings.

A small ribozyme ligase (L1) selected from a random sequence population appears to utilize non-Watson-Crick base pairs at its ligation junction. Mutational and selection analyses confirmed the presence of these base pairings. Randomization of the L1 core and selection of active ligases yielded highl...

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Detaylı Bibliyografya
Asıl Yazarlar: Robertson, M P, Hesselberth, J R, Ellington, A D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2001
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370105/
https://ncbi.nlm.nih.gov/pubmed/11345430
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