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Characterization of the Trans Watson-Crick GU Base Pair Located in the Catalytic Core of the Antigenomic HDV Ribozyme

The HDV ribozyme’s folding pathway is, by far, the most complex folding pathway elucidated to date for a small ribozyme. It includes 6 different steps that have been shown to occur before the chemical cleavage. It is likely that other steps remain to be discovered. One of the most critical of these...

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Autores principales: Lévesque, Dominique, Reymond, Cédric, Perreault, Jean-Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386971/
https://ncbi.nlm.nih.gov/pubmed/22768274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040309
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