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The effect of cytidine on the structure and function of an RNA ligase ribozyme.

A cytidine-free ribozyme with RNA ligase activity was obtained by in vitro evolution, starting from a pool of random-sequence RNAs that contained only guanosine, adenosine, and uridine. This ribozyme contains 74 nt and catalyzes formation of a 3',5'-phosphodiester linkage with a catalytic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rogers, J, Joyce, G F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370096/
https://ncbi.nlm.nih.gov/pubmed/11333020
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