The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

Eukaryotic initiation factor (elF) 4A functions as a subunit of the initiation factor complex elF4F, which mediates the binding of mRNA to the ribosome. elF4A possesses ATPase and RNA helicase activities and is the prototype for a large family of putative RNA helicases (the DEAD box family). It is t...

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Hlavní autoři: Svitkin, Y V, Pause, A, Haghighat, A, Pyronnet, S, Witherell, G, Belsham, G J, Sonenberg, N
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370095/
https://ncbi.nlm.nih.gov/pubmed/11333019
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