Predicting oligonucleotide affinity to nucleic acid targets.

A computer program, OligoWalk, is reported that predicts the equilibrium affinity of complementary DNA or RNA oligonucleotides to an RNA target. This program considers the predicted stability of the oligonucleotide-target helix and the competition with predicted secondary structure of both the targe...

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Detalles Bibliográficos
Autores principales: Mathews, D H, Burkard, M E, Freier, S M, Wyatt, J R, Turner, D H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369867/
https://ncbi.nlm.nih.gov/pubmed/10580474
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