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Hybridization-based affinity partitioning of nucleic acids using PEG-coupled oligonucleotides.

Polyethylene glycol (PEG)-coupled oligonucleotides are partitioned in an aqueous two-phase system PEG/dextran. The affinity of the oligonucleotide for the PEG-rich phase increases proportionally to the length of the coupled PEG polymer. After hybridization, the PEG-coupled oligonucleotide is able to...

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Main Authors: Jäschke, A, Fürste, J P, Erdmann, V A, Cech, D
格式: Artigo
語言:Inglês
出版: 1994
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC308088/
https://ncbi.nlm.nih.gov/pubmed/8208613
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