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Hybridization-based affinity partitioning of nucleic acids using PEG-coupled oligonucleotides.

Polyethylene glycol (PEG)-coupled oligonucleotides are partitioned in an aqueous two-phase system PEG/dextran. The affinity of the oligonucleotide for the PEG-rich phase increases proportionally to the length of the coupled PEG polymer. After hybridization, the PEG-coupled oligonucleotide is able to...

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Udgivet i:Nucleic Acids Res
Principais autores: Jäschke, A, Fürste, J P, Erdmann, V A, Cech, D
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1994
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC308088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8208613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.10.1880
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