Identification and characterization of a novel high affinity metal-binding site in the hammerhead ribozyme.

A novel metal-binding site has been identified in the hammerhead ribozyme by 31P NMR. The metal-binding site is associated with the A13 phosphate in the catalytic core of the hammerhead ribozyme and is distinct from any previously identified metal-binding sites. 31P NMR spectroscopy was used to meas...

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Autori principali: Hansen, M R, Simorre, J P, Hanson, P, Mokler, V, Bellon, L, Beigelman, L, Pardi, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369832/
https://ncbi.nlm.nih.gov/pubmed/10445883
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