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A pseudouridine synthase required for the formation of two universally conserved pseudouridines in ribosomal RNA is essential for normal growth of Escherichia coli.

Escherichia coli rRNA contains 10 pseudouridines of unknown function. They are made by synthases, each of which is specific for one or more pseudouridines. Here we show that the sfhB (yfil) ORF of E. coli is a pseudouridine synthase gene by cloning, protein overexpression, and reaction in vitro with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Raychaudhuri, S, Conrad, J, Hall, B G, Ofengand, J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1998
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369713/
https://ncbi.nlm.nih.gov/pubmed/9814761
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