A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain.

This laboratory previously showed that truncation of the gene for RluD, the Escherichia coli pseudouridine synthase responsible for synthesis of 23S rRNA pseudouridines 1911, 1915, and 1917, blocks pseudouridine formation and inhibits growth. We now show that RluD mutants at the essential aspartate...

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Detalhes bibliográficos
Main Authors: Gutgsell, N S, Del Campo, M D, Raychaudhuri, S, Ofengand, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370151/
https://ncbi.nlm.nih.gov/pubmed/11453071
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