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Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli

Escherichia coli pseudouridine synthase RluD makes pseudouridines 1911, 1915, and 1917 in the loop of helix 69 in 23S RNA. These are the most highly conserved ribosomal pseudouridines known. Of 11 pseudouridine synthases in E. coli, only cells lacking RluD have severe growth defects and abnormal rib...

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Autors principals: DEL CAMPO, MARK, OFENGAND, JAMES, MALHOTRA, ARUN
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2004 by RNA Society 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370535/
https://ncbi.nlm.nih.gov/pubmed/14730022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5187404
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