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Target discrimination by RNA-binding proteins: role of the ancillary protein U2A' and a critical leucine residue in differentiating the RNA-binding specificity of spliceosomal proteins U1A and U2B".

The spliceosomal proteins U1A and U2B" each use a homologous RRM domain to bind specifically to their respective snRNA targets, U1hpll and U2hpIV, two stem-loops that are similar yet distinct in sequence. Previous studies have shown that binding of U2B" to U2hpIV is facilitated by the anci...

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Detaylı Bibliyografya
Asıl Yazarlar: Rimmele, M E, Belasco, J G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369711/
https://ncbi.nlm.nih.gov/pubmed/9814759
Etiketler: Etiketle
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