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Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro.

The splicing reaction that removes introns from pre-messenger RNAs requires the assembly of the spliceosome on the nascent transcript, proper folding of the substrate-enzyme complex, and finally, two transesterification reactions. These stages in the splicing reaction must require careful orchestrat...

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Bibliografski detalji
Glavni autori: Cao, W, Jamison, S F, Garcia-Blanco, M A
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369586/
https://ncbi.nlm.nih.gov/pubmed/9404896
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