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The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation.
SRp20 is a member of the highly conserved SR family of splicing regulators. Using a variety of reporter gene constructs, we show that SRp20 regulates alternative splicing of its own mRNA. Overexpression of SRp20 results in a reduction in the level of exon 4-skipped SRp20 transcripts and activates th...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170142/ https://ncbi.nlm.nih.gov/pubmed/9305649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.5077 |
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