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Crosslinking of the U5 snRNP-specific 116-kDa protein to RNA hairpins that block step 2 of splicing.

Step 2 of pre-mRNA splicing has characteristics that are suggestive of a 5' to 3' scanning process from the branch point to locate the 3' splice site. Specifically, the 3' splice site is almost always at the first AG downstream of the branch point even when the two elements are s...

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Hlavní autoři: Liu, Z R, Laggerbauer, B, Lührmann, R, Smith, C W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369562/
https://ncbi.nlm.nih.gov/pubmed/9409614
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