Smad-dependent GADD45β expression mediates delayed activation of p38 MAP kinase by TGF-β

Transforming growth factor-β (TGF-β), when bound to its specific receptor, activates the transcription factor Smad by phosphorylation. TGF-β also activates the p38 MAPK pathway, but there seem to be disparate mechanisms for the early p38 activation and delayed p38 activation. In this report, we demo...

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Publié dans:	EMBO J
Auteurs principaux:	Takekawa, Mutsuhiro, Tatebayashi, Kazuo, Itoh, Fumio, Adachi, Masaaki, Imai, Kohzoh, Saito, Haruo
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2002
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136947/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456654/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf643
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