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Smad-dependent GADD45β expression mediates delayed activation of p38 MAP kinase by TGF-β

Transforming growth factor-β (TGF-β), when bound to its specific receptor, activates the transcription factor Smad by phosphorylation. TGF-β also activates the p38 MAPK pathway, but there seem to be disparate mechanisms for the early p38 activation and delayed p38 activation. In this report, we demo...

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Udgivet i:EMBO J
Principais autores: Takekawa, Mutsuhiro, Tatebayashi, Kazuo, Itoh, Fumio, Adachi, Masaaki, Imai, Kohzoh, Saito, Haruo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136947/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456654/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf643
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