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FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth
Focal adhesion kinase (FAK) was first identified as a viral Src (v-Src) substrate, but the role of FAK in Src transformation events remains undefined. We show that stable expression of the FAK C-terminal domain (termed FRNK) in v-Src-transformed NIH 3T3 fibroblasts inhibited cell invasion through Ma...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136935/ https://ncbi.nlm.nih.gov/pubmed/12456636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf631 |
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