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Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome
We have determined the human genome to contain 296 different Src homology-3 (SH3) domains and cloned them into a phage-display vector. This provided a powerful and unbiased system for simultaneous assaying of the complete human SH3 proteome for the strongest binding to target proteins of interest, w...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369250/ https://ncbi.nlm.nih.gov/pubmed/16374509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400596 |
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